Meiosis in Humans
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چکیده
Meiosis, the process by which sexually reproducing organisms generate gametes (sex cells), is an essential precondition for the normal formation of the embryo. As sexually-reproducing, diploid, multicellular eukaryotes, humans [5] rely on meiosis [6] to serve a number of important functions, including the promotion of genetic diversity and the creation of proper conditions for reproductive success. However, the primary function of meiosis [6] is the reduction [7] of the ploidy [8] (number of chromosomes) of the gametes from diploid (2n, or two sets of 23 chromosomes) to haploid (1n or one set of 23 chromosomes). While parts of meiosis [6] are similar to mitotic processes, the two systems of cellular division produce distinctly different outcomes. Problems during meiosis [6] can stop embryonic development and sometimes cause spontaneous miscarriages, genetic errors, and birth defects [9] such as Down syndrome [10].
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Meiosis in Humans
Meiosis, the process by which sexually reproducing organisms generate gametes (sex cells), is an essential precondition for the normal formation of the embryo. As sexually-reproducing, diploid, multicellular eukaryotes, humans [5] rely on meiosis [6] to serve a number of important functions, including the promotion of genetic diversity and the creation of proper conditions for reproductive succ...
متن کاملMeiosis in Humans
Meiosis, the process by which sexually reproducing organisms generate gametes (sex cells), is an essential precondition for the normal formation of the embryo. As sexually-reproducing, diploid, multicellular eukaryotes, humans [5] rely on meiosis [6] to serve a number of important functions, including the promotion of genetic diversity and the creation of proper conditions for reproductive succ...
متن کاملMeiosis in Humans
Meiosis, the process by which sexually reproducing organisms generate gametes (sex cells), is an essential precondition for the normal formation of the embryo. As sexually-reproducing, diploid, multicellular eukaryotes, humans [5] rely on meiosis [6] to serve a number of important functions, including the promotion of genetic diversity and the creation of proper conditions for reproductive succ...
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Does cohesion fatigue play a role in the ‘maternal age effect’? The frequency of aneuploid conceptions in humans increases strikingly with maternal age, approaching 35% for women in their 40s. Remarkably, if studies of mouse oocytes are applicable to humans, it appears that the actual cohesin molecules that bind chromatids together in the oocytes of women may be decades old. In mammals, S phase...
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Purpose: The aim of this study was evaluated the effect of β -mercaptoethanol on resumption of meiosis, In vivo maturation of immature mouse oocytes treated with DEHP and embryo development. Materials and Methods: NMRI mouse strain (4-6 weeks) were treated daily with 50,µI DEHP Group 1: 121 immature oocytes were matured in MEM-α medium contain FCS 5%, hCG 7.5 IU/ml, rFsH 100mIU/ml, Group 2: 12...
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